Lungs Involved in Challenging Role of Making Blood

We all know that blood is solely produced in bone marrow. Bone marrow has been proposed to be a major site of platelet production. But it is now turned to be a wrong answer. Recent studies on mice at the University of California San Francisco have found that the greater number of platelets is produced in the lungs, as is a backup reservoir of blood stem cells which can step when bone marrow is running short of platelets. And so it seems to be a bit of cooperation going on between lungs and bone marrow to make blood.

The lungs aid in respiration acting as oxygen carrier. Lungs also help the body to get rid of CO2 gas when we breathe out. Lungs are the only site in our body where blood picks up oxygen. Lungs are the organs which have capability to float on water. Our machine still hold plenty of secrets, The UCSF study discovered the new role of lungs while investigating the interaction of lungs with immune system through imaging techniques. The mice in question had been engineered so that their platelets emit bright green fluorescence which highlighted a surprising number of megakaryocytes in the organs.

It’s really fascinating to know that megakaryocytes travel all the way from bone marrow to lungs for platelet production. If this finding of discovery about the lung’s role in blood production occurs in humans, it could provide new approaches for treating blood diseases.

This also opens novel studies into treatments for diseases that affect platelet production, also provides a better understanding of the active role stem cells play in the body. Future research could apply the discovery to the human machine, and work on how the lungs and bone marrow work together to produce blood.

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